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Article

Protein Z and Endothelin-1 genetic polymorphisms in pediatric Egyptian sickle cell disease patients.

Journal of clinical laboratory analysis - 1 Feb 2018

Khorshied Mervat M, Mohamed Nohair S, Hamza Rania S, Ali Rasha M, El-Ghamrawy Mona K

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) is a monogenic disease associated with multisystem morbidity. Vasculopathy caused by delicate imbalance between coagulation and endothelial systems plays a pivotal role in disease course. As Protein Z and Endothelin-1 genetic polymorphisms may increase the thrombotic risk, the aim of the current work was to verify the possible impact of Protein Z (PROZ G79A) and Endothelin-1...

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Topics

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Share to Adolescent
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Proteins

Share to Child, Preschool

Share to Endothelin-1

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 28548215
DOI: 10.1002/jcla.22264
PMCID: PMC6816928

Genes

SCD
EDN1
PROZ

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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