Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Schwann cells exhibit long‐term cell survival, are not tumorigenic and promote repair when transplanted into the contused spinal cord

22 May 2017

Abstract excerpt

The transplantation of rodent Schwann cells (SCs) provides anatomical and functional restitution in a variety of spinal cord injury (SCI) models, supporting the recent translation of SCs to phase 1 clinical trials for human SCI. Whereas human (Hu)SCs have been examined experimentally in a complete SCI transection paradigm, to date the reported behavior of SCs when transplanted after a clinically relevant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nerve injury and regeneration
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28543541
DOI: 10.1002/glia.23161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Schwann cells exhibit long‐term cell survival, are not tumorigenic and promote repair when transplanted into the contused spinal cordPMID 28543541Read ↗

Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem CellsSemantic proximity Read ↗

Human Schwann cells retain essential phenotype characteristics after immortalization.Semantic proximity Read ↗

Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: Survival, migration, axon association, and functional recovery.Semantic proximity Read ↗

The properties of human Schwann cells: Lessons from in vitro culture and transplantation studiesSemantic proximity Read ↗

Cell Transplantation for Spinal Cord Injury: Tumorigenicity of Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor CellsSemantic proximity Read ↗

Directly induced human Schwann cell precursors as a valuable source of Schwann cellsSemantic proximity Read ↗

Survival, integration, and axon growth support of glia transplanted into the chronically contused spinal cord.Semantic proximity Read ↗

Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats.Semantic proximity Read ↗

Preclinical Safety of Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Supporting Clinical Trials in Spinal Cord InjurySemantic proximity Read ↗

Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury.Semantic proximity Read ↗

Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury.Semantic proximity Read ↗

Transplantation of Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors into Rat Spinal Cord Injuries Does not Cause HarmSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.