Article
A technique for setting analytical thresholds in massively parallel sequencing-based forensic DNA analysis.
PloS one - 1 Jan 2017
Young Brian, King Jonathan L, Budowle Bruce, Armogida Luigi
Abstract excerpt
Amplicon (targeted) sequencing by massively parallel sequencing (PCR-MPS) is a potential method for use in forensic DNA analyses. In this application, PCR-MPS may supplement or replace other instrumental analysis methods such as capillary electrophoresis and Sanger sequencing for STR and mitochondrial DNA typing, respectively. PCR-MPS also may enable the expansion of forensic DNA analysis methods to include new...
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