Article
Inter-laboratory study on standardized MPS libraries: evaluation of performance, concordance, and sensitivity using mixtures and degraded DNA.
International journal of legal medicine - 1 Jan 2020
Müller Petra, Sell Christian, Hadrys Thorsten, Hedman Johannes, Bredemeyer Steffi, Laurent Francois-Xavier, Roewer Lutz, Achtruth Sabrina, Sidstedt Maja, Sijen Titia, Trimborn Marc, Weiler Natalie, Willuweit Sascha, Bastisch Ingo, Parson Walther
Abstract excerpt
We present results from an inter-laboratory massively parallel sequencing (MPS) study in the framework of the SeqForSTRs project to evaluate forensically relevant parameters, such as performance, concordance, and sensitivity, using a standardized sequencing library including reference material, mixtures, and ancient DNA samples. The standardized library was prepared using the ForenSeq DNA Signature Prep Kit...
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