Article
The Role and Mechanism of Erythrocyte Invasion by Francisella tularensis.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Schmitt Deanna M, Barnes Rebecca, Rogerson Taylor, Haught Ashley, Mazzella Leanne K, Ford Matthew, Gilson Tricia, Birch James W-M, Sjöstedt Anders, Reed Douglas S, Franks Jonathan M, Stolz Donna B, Denvir James, Fan Jun, Rekulapally Swanthana, Primerano Donald A, Horzempa Joseph
Abstract excerpt
Francisella tularensis is an extremely virulent bacterium that can be transmitted naturally by blood sucking arthropods. During mammalian infection, F. tularensis infects numerous types of host cells, including erythrocytes. As erythrocytes do not undergo phagocytosis or endocytosis, it remains unknown how F. tularensis invades these cells. Furthermore, the consequence of inhabiting the intracellular space of red...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.