Article
MicroRNA-135a-3p is downregulated and serves as a tumour suppressor in ovarian cancer by targeting CCR2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2018
Duan Shufeng, Dong Xuecai, Hai Jing, Jiang Jinghong, Wang Wenxiang, Yang Jing, Zhang Wei, Chen Caixia
Abstract excerpt
MicroRNAs have been demonstrated to play a crucial role in the development of ovarian cancer. Many studies prove that forms of miR-135a, including miR-135a-5p and miR-135a-3p, serve as tumour suppressors in multiple cancers. Nevertheless, the precise function of miR-135a-3p and the molecular mechanisms underlying the involvement of miR-135a-3p in ovarian carcinoma cell growth and metastasis remain largely...
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