Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 months

22 May 2017

Abstract excerpt

If humans ever start to live permanently in space, assisted reproductive technology using preserved spermatozoa will be important for producing offspring; however, radiation on the International Space Station (ISS) is more than 100 times stronger than that on Earth, and irradiation causes DNA damage in cells and gametes. Here we examined the effect of space radiation on freeze-dried mouse spermatozoa held on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Spaceflight effects on biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28533361
DOI: 10.1073/pnas.1701425114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 monthsPMID 28533361Read ↗

Development of mouse preimplantation embryos in spaceSemantic proximity Read ↗

Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes.Semantic proximity Read ↗

Comparison of biological measurement and physical estimates of space radiation in the International Space StationSemantic proximity Read ↗

Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1Semantic proximity Read ↗

Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location.Semantic proximity Read ↗

Healthy cloned offspring derived from freeze-dried somatic cellsSemantic proximity Read ↗

A Brief Overview of Radiation-Induced Effects on Spermatogenesis and OncofertilitySemantic proximity Read ↗

Characterization of unstable microsatellites in mice: no evidence for germline mutation induction following gamma-radiation exposure.Semantic proximity Read ↗

Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells.Semantic proximity Read ↗

Metabolic stress in space: ROS-induced mutations in mice hint at a new path to cancer.Semantic proximity Read ↗

Sub-chronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in miceSemantic proximity Read ↗

Three major reasons why transgenerational effects of radiation are difficult to detect in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.