Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1

Abstract excerpt

Genetic and environmental factors produce different levels of DNA damage in spermatozoa. Usually, DNA-fragmented spermatozoa (DFS) are used with intracytoplasmic sperm injection (ICSI) treatments in human reproduction, and use of DFS is still a matter of concern. The purpose of the present study was to investigate the long-term consequences on development and behavior of mice generated by ICSI with DFS. Using CD1...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Assisted Reproductive Technology and Twin Pregnancy
• Share to Prenatal Screening and Diagnostics
• Share to Reproductive Biology and Fertility