Article
Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients.
Respiratory research - 22 May 2017
Loi Adèle Lo Tam, Hoonhorst Susan, van Aalst Corneli, Langereis Jeroen, Kamp Vera, Sluis-Eising Simone, Ten Hacken Nick, Lammers Jan-Willem, Koenderman Leo
Abstract excerpt
BACKGROUND: COPD is a heterogeneous chronic inflammatory disease of the airways and it is well accepted that the GOLD classification does not fully represent the complex clinical manifestations of COPD and this classification therefore is not well suited for phenotyping of individual patients with COPD. Besides the chronic inflammation in the lung compartment, there is also a systemic inflammation present in COPD...
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