Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammatory discordance phenotype in COPD: Dissociation between neutrophil-to-lymphocyte ratio and conventional markers.

PloS one - 1 Jan 2026

Colakoglu Can, Ozsahin Sefa Levent

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder with diverse inflammatory profiles. Long-term oxygen therapy (LTOT) identifies a subgroup of patients with advanced disease; however, the systemic inflammatory characteristics of this population remain incompletely defined. OBJECTIVE: To investigate systemic inflammatory markers in clinically stable COPD patients according to...

Read the complete abstract on PubMed

Topics

Humans
Pulmonary Disease, Chronic Obstructive
Neutrophils
Male
Female
Lymphocytes
Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Aged

Leukocyte Count

Phenotype

C-Reactive Protein

Inflammation

Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42726765
DOI: 10.1371/journal.pone.0357923
PMCID: PMC13567818

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammatory discordance phenotype in COPD: Dissociation between neutrophil-to-lymphocyte ratio and conventional markers.PMID 42726765Read ↗

Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.Semantic proximity Read ↗

Blood Cell Ratio Biomarkers of Non-type 2 Inflammation in Chronic Obstructive PulmonarySemantic proximity Read ↗

Characteristics of inflammatory phenotypes in patients with chronic obstructive pulmonary disease: a cross-sectional study.Semantic proximity Read ↗

Blood cell for the differentiation of airway inflammatory phenotypes in COPD exacerbations.Semantic proximity Read ↗

Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients.Semantic proximity Read ↗

[COPD and inflammation: statement from a French expert group. Phenotypes related to inflammation].Semantic proximity Read ↗

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Systemic biomarkers in the evaluation and management of COPD patients: are we getting closer to clinical application?Semantic proximity Read ↗

Neutrophil phenotypes in chronic lung diseaseSemantic proximity Read ↗

Inflammatory phenotype drives different immunosuppressive response in COPD exacerbations.Semantic proximity Read ↗

Association Between Routine Blood Biomarkers and Clinical Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

[Systemic and lung inflammation in 2 phenotypes of chronic obstructive pulmonary disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.