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Article

COMT-Val158Met-polymorphism is not a risk factor for acute kidney injury after cardiac surgery.

Disease markers - 1 Jan 2013

Kornek Matthias, Deutsch Marcus-André, Eichhorn Stefan, Lahm Harald, Wagenpfeil Stefan, Krane Markus, Lange Ruediger, Boehm Johannes

Abstract excerpt

BACKGROUND: Cardiac surgery-associated acute kidney injury (CSA-AKI) depicts a major complication after cardiac surgery using cardiopulmonary bypass (CPB). OBJECTIVE: CSA-AKI has clearly been linked to increased perioperative morbidity and mortality. Dysregulations of vasomotor tone are assumed to be causal for CSA-AKI. While catechol-O-methyltransferase (COMT) is involved in metabolizing catecholamines, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24167357
DOI: 10.1155/2013/279046
PMCID: PMC3774963

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

COMT-Val158Met-polymorphism is not a risk factor for acute kidney injury after cardiac surgery.PMID 24167357Read ↗

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Decreased catecholamine degradation associates with shock and kidney injury after cardiac surgery.Semantic proximity Read ↗

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Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians.Semantic proximity Read ↗

Effects of β-Adrenoceptor and Catechol-O-Methyl-Transferase (COMT) Polymorphism on Postoperative Outcome in Cardiac Surgery Patients.Semantic proximity Read ↗

Influence of ADRB1, ADRB2, and COMT Genetic Polymorphisms on Postoperative Outcomes of Patients Undergoing Cardiac Valve Surgery.Semantic proximity Read ↗

Chronic persistent surgical pain is strongly associated with COMT alleles in patients undergoing cardiac surgery with median sternotomy.Semantic proximity Read ↗

The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery.Semantic proximity Read ↗

The eNOS 786C/T polymorphism in cardiac surgical patients with cardiopulmonary bypass is associated with renal dysfunction.Semantic proximity Read ↗

Unraveling the Role of COMT Polymorphism in Dopamine-Mediated Vasopressor Effects: An Observational Cross-Sectional Study.Semantic proximity Read ↗

Epidemiology and pathophysiology of cardiac surgery-associated acute kidney injury.Semantic proximity Read ↗

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