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Article

Modeling the dynamics of mouse iron body distribution: hepcidin is necessary but not sufficient.

BMC systems biology - 18 May 2017

Parmar Jignesh H, Davis Grey, Shevchuk Hope, Mendes Pedro

Abstract excerpt

BACKGROUND: Iron is an essential element of most living organisms but is a dangerous substance when poorly liganded in solution. The hormone hepcidin regulates the export of iron from tissues to the plasma contributing to iron homeostasis and also restricting its availability to infectious agents. Disruption of iron regulation in mammals leads to disorders such as anemia and hemochromatosis, and contributes to...

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Identifiers

PMID: 28521769
DOI: 10.1186/s12918-017-0431-3
PMCID: PMC5437513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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