Article
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.
Journal for immunotherapy of cancer - 1 Jan 2017
Gnjatic Sacha, Bronte Vincenzo, Brunet Laura Rosa, Butler Marcus O, Disis Mary L, Galon Jérôme, Hakansson Leif G, Hanks Brent A, Karanikas Vaios, Khleif Samir N, Kirkwood John M, Miller Lance D, Schendel Dolores J, Tanneau Isabelle, Wigginton Jon M, Butterfield Lisa H
Abstract excerpt
As cancer strikes, individuals vary not only in terms of factors that contribute to its occurrence and development, but as importantly, in their capacity to respond to treatment. While exciting new therapeutic options that mobilize the immune system against cancer have led to breakthroughs for a variety of malignancies, success is limited to a subset of patients. Pre-existing immunological features of both the...
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