Article
Immunological-based approaches for cancer therapy.
Clinics (Sao Paulo, Brazil) - 20 Aug 2018
Barros Luciana, Pretti Marco Antonio, Chicaybam Leonardo, Abdo Luiza, Boroni Mariana, Bonamino Martin Hernán
Abstract excerpt
The immunologic landscape of tumors has been continuously unveiled, providing a new look at the interactions between cancer cells and the immune system. Emerging tumor cells are constantly eliminated by the immune system, but some cells establish a long-term equilibrium phase leading to tumor immunoediting and, eventually, evasion. During this process, tumor cells tend to acquire more mutations. Bearing a high...
Topics
- Antigens, Neoplasm
- Cancer Vaccines
- Cell Transformation, Neoplastic
- Combined Modality Therapy
- Genetic Therapy
- Humans
- Immunotherapy
- Mutation
- Neoplasms
- Tumor Escape
- Tumor Microenvironment