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Article

Mendelian randomization shows sex-specific associations between long-chain PUFA-related genotypes and cognitive performance in Danish schoolchildren.

The American journal of clinical nutrition - 1 Jul 2017

Lauritzen Lotte, Sørensen Louise B, Harsløf Laurine B, Ritz Christian, Stark Ken D, Astrup Arne, Dyssegaard Camilla B, Egelund Niels, Michaelsen Kim F, Damsgaard Camilla T

Abstract excerpt

Background: Dietary and endogenously formed long-chain polyunsaturated fatty acids (LCPUFAs) are hypothesized to improve cognitive development, but results are inconclusive, with suggestions of sex specificity. One study suggested that single-nucleotide polymorphisms (SNPs) rs1535 and rs174448 in the fatty acid desaturase (FADS) gene cluster have opposite effects on erythrocyte LCPUFAs at 9 mo.Objective: To...

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Source

Identifiers

PMID: 28515069
DOI: 10.3945/ajcn.117.152595

Genes

ELOVL5
FADS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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