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Article

Patterns of perinatal exposure to PUFAs and child neurodevelopment: evidence from Mendelian randomization using FADS cluster variants.

The American journal of clinical nutrition - 1 Jul 2025

Abou Assi Aline, Armand Martine, Sarté Catherine, Tafflet Muriel, Yuan Wen Lun, Peyre Hugo, Charles Marie-Aline, Heude Barbara, Bernard Jonathan Y

Abstract excerpt

BACKGROUND: The potential causal effects of perinatal exposure to polyunsaturated fatty acids (PUFAs) on child neurodevelopment remains controversial. OBJECTIVE: To infer causation, we assessed the association of perinatal PUFA patterns and child neurodevelopment by using conventional regression analyses and 1-sample Mendelian randomization (MR). METHODS: Among 1096 mother-child pairs from the French Etude des...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40610128
DOI: 10.1016/j.ajcnut.2025.03.014

Genes

FADS1
FADS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Patterns of perinatal exposure to PUFAs and child neurodevelopment: evidence from Mendelian randomization using FADS cluster variants.PMID 40610128Read ↗

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