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Structural and functional characterization of SidF, a possible dual substrate <i>Aspergillus fumigatus</i> N5-acetyl-N5-hydroxy-L-ornithine transacetylase

2024-08-04

Abstract excerpt

Siderophore-mediated iron acquisition is essential for the virulence of Aspergillus fumigatus , a fungus causing life-threatening aspergillosis. Developing drugs targeting the siderophore biosynthetic pathway could help improve disease management. The transacetylases SidF and SidL generate intermediates for different siderophores in A. fumigatus . A. fumigatus has a yet unidentified transacetylase that compleme...

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Literature Corpus work
04fd78d0-6115-5082-98d1-2768d23bb83a
DOI
10.1101/2024.08.03.606473
Open publication

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Structural and functional characterization of SidF, a possible dual substrate <i>Aspergillus fumigatus</i> N5-acetyl-N5-hydroxy-L-ornithine transacetylaseDOI 10.1101/2024.08.03.606473
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