Article
FecX Bar a Novel BMP15 mutation responsible for prolificacy and female sterility in Tunisian Barbarine Sheep.
BMC genetics - 15 May 2017
Lassoued Narjess, Benkhlil Zohra, Woloszyn Florent, Rejeb Ahmed, Aouina Mohamed, Rekik Mourad, Fabre Stephane, Bedhiaf-Romdhani Sonia
Abstract excerpt
BACKGROUND: Naturally occurring mutations in growth and differentiation factor 9 (GDF9) or bone morphogenetic protein 15 (BMP15) genes are associated with increased ovulation rate (OR) and litter size (LS) but also sterility. Observing the Tunisian Barbarine ewes of the "W" flock selected for improved prolificacy, we found prolific and infertile ewes with streaky ovaries. Blood genomic DNA was extracted from a...
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