Article
Screening for causative mutations in ovine BMPR1B and BMP15 genes and their homologous fragments in human.
Journal of assisted reproduction and genetics - 1 Aug 2023
Zamani Pouya, Rabiei Fatemeh, Hadiei Elahe, Abdoli Ramin, Ahmadi Ahmad, Rabiei Soghra
Abstract excerpt
PURPOSE: The BMPR1B and BMP15 genes are well known for their considerable associations with prolificacy in sheep. These genes may also affect fertility or prolificacy in other species, including human. This study was conducted to investigate possible causative mutations in BMPR1B and BMP15 genes in human and an indigenous breed of sheep. METHODS: Blood samples were collected from 83 singleton- and prolific...
Topics
- Pregnancy
- Sheep
- Humans
- Animals
- Female
- Mutation
- Fertility
- Litter Size
- Alleles
- Base Sequence
- Genotype
- Bone Morphogenetic Protein Receptors, Type I
