Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep.

PLoS genetics - 1 Apr 2013

Demars Julie, Fabre Stéphane, Sarry Julien, Rossetti Raffaella, Gilbert Hélène, Persani Luca, Tosser-Klopp Gwenola, Mulsant Philippe, Nowak Zuzanna, Drobik Wioleta, Martyniuk Elzbieta, Bodin Loys

Abstract excerpt

Some sheep breeds are naturally prolific, and they are very informative for the studies of reproductive genetics and physiology. Major genes increasing litter size (LS) and ovulation rate (OR) were suspected in the French Grivette and the Polish Olkuska sheep populations, respectively. To identify genetic variants responsible for the highly prolific phenotype in these two breeds, genome-wide association studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein 15
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Litter Size

Share to Mutation

Share to Ovulation

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 23637641
DOI: 10.1371/journal.pgen.1003482
PMCID: PMC3636084

Genes

BMP15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep.PMID 23637641Read ↗

A new allele in the BMP15 gene (FecXRA) that affects prolificacy co-segregates with FecXR and FecXGR in Rasa aragonesa sheep.Semantic proximity Read ↗

Genome-wide identification of a regulatory mutation in <i>BMP15</i> controlling prolificacy in sheepSemantic proximity Read ↗

Screening for causative mutations in ovine BMPR1B and BMP15 genes and their homologous fragments in human.Semantic proximity Read ↗

Screening for Causative Mutations of Major Prolificacy Genes in Iranian Fat-Tailed Sheep.Semantic proximity Read ↗

FecX Bar a Novel BMP15 mutation responsible for prolificacy and female sterility in Tunisian Barbarine Sheep.Semantic proximity Read ↗

Effects of novel variants in BMP15 gene on litter size in Mongolia and Ujimqin sheep breeds.Semantic proximity Read ↗

Genome-wide association study to identify genomic regions affecting prolificacy in Lori-Bakhtiari sheep.Semantic proximity Read ↗

Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner.Semantic proximity Read ↗

Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency.Semantic proximity Read ↗

Fecundity genes in sheep.Semantic proximity Read ↗

Novel Mutation in Exon 1 of the BMP15 Gene and its Association with Reproduction Traits in Sheep.Semantic proximity Read ↗

A Novel Mutation in the Bone Morphogenetic Protein 15 Gene Causing Defective Protein Secretion Is Associated with Both Increased Ovulation Rate and Sterility in Lacaune SheepSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.