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Article

SODA: prediction of protein solubility from disorder and aggregation propensity.

Nucleic acids research - 3 Jul 2017

Paladin Lisanna, Piovesan Damiano, Tosatto Silvio C E

Abstract excerpt

Solubility is an important, albeit not well understood, feature determining protein behavior. It is of paramount importance in protein engineering, where similar folded proteins may behave in very different ways in solution. Here we present SODA, a novel method to predict the changes of protein solubility based on several physico-chemical properties of the protein. SODA uses the propensity of the protein sequence...

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Identifiers

PMID: 28505312
DOI: 10.1093/nar/gkx412
PMCID: PMC7059794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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