Article
Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer.
Breast cancer research and treatment - 1 Aug 2017
Maxwell Kara N, Soucier-Ernst Danielle, Tahirovic Emin, Troxel Andrea B, Clark Candace, Feldman Michael, Colameco Christopher, Kakrecha Bijal, Langer Melissa, Lieberman David, Morrissette Jennifer J D, Paul Matt R, Pan Tien-Chi, Yee Stephanie, Shih Natalie, Carpenter Erica, Chodosh Lewis A, DeMichele Angela
Abstract excerpt
PURPOSE: Breast cancer metastases differ biologically from primary disease; therefore, metastatic biopsies may assist in treatment decision making. Commercial genomic testing of both tumor and circulating tumor DNA have become available clinically, but utility of these tests in breast cancer management remains unclear. METHODS: Patients undergoing a clinically indicated metastatic tumor biopsy were consented to...
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