Article
CPAM type 2-derived mesenchymal stem cells: Malignancy risk study in a 14-month-old boy.
Pediatric pulmonology - 1 Aug 2017
Pelizzo Gloria, Avanzini Maria A, Folini Marco, Bussani Rossana, Mantelli Melissa, Croce Stefania, Acquafredda Gloria, Travaglino Paola, Cimino-Reale Graziella, Boni Marina, Dambruoso Irene, Calcaterra Valeria
Abstract excerpt
INTRODUCTION: The association between congenital pulmonary airway malformations (CPAM) and malignancy is reported in the literature. Interactions between the tumor, immune, and mesenchymal stromal/stem cells (MSCs) have been recognized as crucial for understanding tumorigenesis. We characterized MSCs isolated from CPAM lesions in order to define potential malignancy risks. METHODS: CPAM II pulmonary tissue was...
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