Cancer-associated Mutations in Congenital Pulmonary Malformations: A Prospective Cohort

Abstract excerpt

To the Editor:Cancer-associated mutations are identified in some congenital pulmonary malformations (CPMs), including mutations of the V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) gene in particular (1, 2).They were described in cystic malformations, with or without mucinous islets (1, 2).The theoretical risk of a link between CPMs and cancer risk is fueling the debate about whether preventive...

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