Article
Role of habenula and amygdala dysfunction in Parkinson disease patients with punding.
Neurology - 6 Jun 2017
Markovic Vladana, Agosta Federica, Canu Elisa, Inuggi Alberto, Petrovic Igor, Stankovic Iva, Imperiale Francesca, Stojkovic Tanja, Kostic Vladimir S, Filippi Massimo
Abstract excerpt
OBJECTIVE: To assess whether a functional dysregulation of the habenula and amygdala, as modulators of the reward brain circuit, contributes to Parkinson disease (PD) punding. METHODS: Structural and resting-state functional MRI were obtained from 22 patients with PD punding, 30 patients with PD without any impulsive-compulsive behavior (ICB) matched for disease stage and duration, motor impairment, and cognitive...
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