Article
Enhanced circulating ILC2s accompany by upregulated MDSCs in patients with asthma.
International journal of clinical and experimental pathology - 1 Jan 2015
Wu Yumin, Yan Yulan, Su Zhaoliang, Bie Qingli, Wu Jing, Wang Shengjun, Yu Ying, Ding Hongqun, Lu Ping, Xu Huaxi
Abstract excerpt
Group 2 innate lymphoid cells (ILC2s) are considered to be the most significant mediators during the orchestration of immune responses in asthma. Myeloid-derived suppressor cells (MDSCs) has received a great deal of attention for their immunosuppressive activity, and our early studies indicate that the increased Th2 cytokines are associated with MDSCs. In this study, we sought to determine whether MDSCs are also...
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