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Article

Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.

The Journal of biological chemistry - 16 Jun 2017

Ye Feng, Yang Chansik, Kim Jiyoon, MacNevin Christopher J, Hahn Klaus M, Park Dongeun, Ginsberg Mark H, Kim Chungho

Abstract excerpt

Epigallocatechin gallate (EGCG) is the principal bioactive ingredient in green tea and has been reported to have many health benefits. EGCG influences multiple signal transduction pathways related to human diseases, including redox, inflammation, cell cycle, and cell adhesion pathways. However, the molecular mechanisms of these varying effects are unclear, limiting further development and utilization of EGCG as a...

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PMID: 28487468
DOI: 10.1074/jbc.C117.787309
PMCID: PMC5473239

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EGFR
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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