Article
Soft Sweeps Are the Dominant Mode of Adaptation in the Human Genome.
Molecular biology and evolution - 1 Aug 2017
Schrider Daniel R, Kern Andrew D
Abstract excerpt
The degree to which adaptation in recent human evolution shapes genetic variation remains controversial. This is in part due to the limited evidence in humans for classic "hard selective sweeps", wherein a novel beneficial mutation rapidly sweeps through a population to fixation. However, positive selection may often proceed via "soft sweeps" acting on mutations already present within a population. Here, we...
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