Article
Classic selective sweeps were rare in recent human evolution.
Science (New York, N.Y.) - 18 Feb 2011
Hernandez Ryan D, Kelley Joanna L, Elyashiv Eyal, Melton S Cord, Auton Adam, McVean Gilean, Sella Guy, Przeworski Molly
Abstract excerpt
Efforts to identify the genetic basis of human adaptations from polymorphism data have sought footprints of "classic selective sweeps" (in which a beneficial mutation arises and rapidly fixes in the population).Yet it remains unknown whether this form of natural selection was common in our evolution. We examined the evidence for classic sweeps in resequencing data from 179 human genomes. As expected under a...
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