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Article

The lens as a model for fibrotic disease

14 Mar 2011

Abstract excerpt

Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the development of appropriate therapeutic strategies. The lens is an elegant experimental model to study the processes that give rise to fibrosis. The molecular and...

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PMID: 21402588
DOI: 10.1098/rstb.2010.0341

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