Article
The peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations in bronchoscopic cytological specimens of non-small cell lung cancer.
Oncology - 1 Jan 2012
Yamada Noriyuki, Oizumi Satoshi, Asahina Hajime, Shinagawa Naofumi, Kikuchi Eiki, Kikuchi Junko, Sakakibara-Konishi Jun, Tanaka Tomoaki, Kobayashi Kunihiko, Hagiwara Koichi, Nishimura Masaharu
Abstract excerpt
OBJECTIVES: Cytological examination of samples obtained by bronchoscopy is a useful method for establishing the diagnosis of non-small cell lung cancer (NSCLC). However, the utility of a highly sensitive method for the detection of epidermal growth factor receptor (EGFR) mutation in the cytological specimens has not been fully evaluated. METHODS: We retrospectively examined the efficacy of the peptide nucleic...
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