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Article

Association of Catechol-O-methyltransferase polymorphism Val158Met and mammographic density: A meta-analysis.

Gene - 15 Aug 2017

Kallionpää Roope A, Uusitalo Elina, Peltonen Juha

Abstract excerpt

OBJECTIVES: The Val158Met polymorphism in catechol-O-methyltransferase (COMT) enzyme reduces the methylation of catechol estrogens, which may affect mammographic density. High mammographic density is a known risk factor of breast cancer. Our aim was to perform meta-analysis of the effect of COMT Val158Met polymorphism on mammographic density. METHODS: Original studies reporting data on mammographic density,...

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Source

Identifiers

PMID: 28473194
DOI: 10.1016/j.gene.2017.04.049

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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