Article
Breast density and polymorphisms in genes coding for CYP1A2 and COMT: the Multiethnic Cohort.
BMC cancer - 12 Feb 2007
Takata Yumie, Maskarinec Gertraud, Le Marchand Loïc
Abstract excerpt
BACKGROUND: Mammographic density is a strong predictor of breast cancer risk and is increased by hormone replacement therapy (HRT). Some associations with genetic polymorphisms in enzymes involved in estrogen metabolism have been described. This cross-sectional analysis examined the relation between mammographic density and the CYP1A2*1F and COMT Val58 Met polymorphisms among 332 breast cancer cases and 254...
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