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Article

Fgf21 is required for cardiac remodeling in pregnancy.

Cardiovascular research - 1 Nov 2017

Redondo-Angulo Ibon, Mas-Stachurska Aleksandra, Sitges Marta, Tinahones Francisco José, Giralt Marta, Villarroya Francesc, Planavila Anna

Abstract excerpt

AIMS: Fibroblast growth factor-21 (Fgf21) is an endocrine factor that contributes to many physiological and pathological processes, mainly via its action as a metabolic regulator. Recent studies have shown that Fgf21 plays an important role in cardiac tissue. Pregnancy offers a physiological model of adaptive and reversible heart enlargement, but the molecular mechanisms underlying this cardiac hypertrophy are...

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Source

Identifiers

PMID: 28472473
DOI: 10.1093/cvr/cvx088

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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