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Article

Associations of GATA4 genetic mutations with the risk of congenital heart disease: A meta-analysis.

Medicine - 1 May 2017

Zhang Yanwei, Ai Feng, Zheng Jiayong, Peng Bangtian

Abstract excerpt

BACKGROUND: GATA4 gene is a cardiac transcriptional factor playing important role in cardiac formation and development. Three GATA4 gene mutations, 99 G>T, 487 C>T, and 354 A>C, have been reported in congenital heart disease (CHD). Therefore, a meta-analysis was performed to explore the associations between 99 G>T, 487 C>T, or 354 A>C mutations and the risk of CHD. METHODS: We searched the relevant studies in...

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Source

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Identifiers

PMID: 28471988
DOI: 10.1097/MD.0000000000006857
PMCID: PMC5419936

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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