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Article

p63+ ureteric bud tip cells are progenitors of intercalated cells

3 May 2017

Abstract excerpt

During renal branching morphogenesis, ureteric bud tip cells (UBTC) serve as the progenitor epithelium for all cell types of the collecting duct. While the transcriptional circuitry of ureteric bud (UB) branching has been intensively studied, the transcriptional control of UBTC differentiation has been difficult to ascertain. This is partly due to limited knowledge of UBTC-specific transcription factors that mark...

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PMID: 28469077
DOI: 10.1172/jci.insight.89996

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