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Article

Granulocytic myeloid derived suppressor cells expand in human pregnancy and modulate T ‐cell responses

3 Jun 2014

Abstract excerpt

Immune tolerance toward the semiallogeneic fetus plays a crucial role in the maintenance of pregnancy. Myeloid-derived suppressor cells (MDSCs) are innate immune cells characterized by their ability to modulate T-cell responses. Recently, we showed that MDSCs accumulate in cord blood of healthy newborns, yet their role in materno-fetal tolerance remained elusive. In the present study, we demonstrate that MDSCs...

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PMID: 24894988
DOI: 10.1002/eji.201344200

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