Cholesterol in the Pathogenesis of Alzheimer’s, Parkinson’s Diseases and Autism: Link to Synaptic Dysfunction

Abstract excerpt

In our previous review, we described brain cholesterol metabolism in control conditions and in the case of some rare neurological pathologies linked to defects in the genes which are directly involved in the synthesis and/or traffic of cholesterol. Here, we have analyzed disruptions in cholesterol homeostasis in widespread neurodegenerative diseases (Alzheimer's and Parkinson's diseases) and autism spectrum...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cholesterol and Lipid Metabolism
• Share to Lipid Membrane Structure and Behavior
• Share to Receptor Mechanisms and Signaling