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Article

Use of Histone K-M Mutants for the Analysis of Transcriptional Regulation in Mouse Zygotes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Aoshima Keisuke, Kimura Takashi, Okada Yuki

Abstract excerpt

Histone modifications are dramatically altered during the pronuclear (PN) stage of zygotes, and more markedly in paternal than maternal pronuclei. Among various types of histone modifications, lysine methylation exhibits the most dynamic changes in the PN stage . To analyze the physiological functions of histone methylations, it is therefore important to elucidate the mechanism of epigenetic reprogramming....

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PMID: 28456971
DOI: 10.1007/978-1-4939-6988-3_18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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