Article
Peroxisome proliferator-activated receptor-γ agonists attenuate biofilm formation by Pseudomonas aeruginosa.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2017
Bedi Brahmchetna, Maurice Nicholas M, Ciavatta Vincent T, Lynn K Sabrina, Yuan Zhihong, Molina Samuel A, Joo Myungsoo, Tyor William R, Goldberg Joanna B, Koval Michael, Hart C Michael, Sadikot Ruxana T
Abstract excerpt
Pseudomonas aeruginosa is a significant contributor to recalcitrant multidrug-resistant infections, especially in immunocompromised and hospitalized patients. The pathogenic profile of P. aeruginosa is related to its ability to secrete a variety of virulence factors and to promote biofilm formation. Quorum sensing (QS) is a mechanism wherein P. aeruginosa secretes small diffusible molecules, specifically acyl...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
