Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of a variant form of vasoactive intestinal polypeptide.

Peptides - 1 Jan 2000

Gafvelin G, Andersson M, Dimaline R, Jörnvall H, Mutt V

Abstract excerpt

A variant form of the vasoactive intestinal polypeptide (VIP) has been isolated. It was found to consist of a molecule which instead of the C-terminal asparagine amide of VIP has a C-terminal extension of Gly-Lys-Arg. This VIP variant displaces VIP in a VIP receptor assay, reacts with N-terminally-directed antisera in a VIP radioimmunoassay and possesses VIP-like bioactivity in an assay measuring pancreatic juice...

Topics

Amino Acids
Animals
Binding, Competitive
Cats
Cell Membrane
Chromatography, High Pressure Liquid
Chromatography, Ion Exchange
Genetic Variation
Liver
Pancreatic Juice
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Gastrointestinal Hormone

Receptors, Vasoactive Intestinal Peptide

Vasoactive Intestinal Peptide

Source

Identifiers

PMID: 2843830
DOI: 10.1016/0196-9781(88)90149-0

Genes

VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2843830-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Isolation and characterization of a variant form of vasoactive intestinal polypeptide.PMID 2843830Read ↗

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal systemSemantic proximity Read ↗

A natural variant type II G protein-coupled receptor for vasoactive intestinal peptide with altered function.Semantic proximity Read ↗

Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's disease.Semantic proximity Read ↗

Molecular cloning, characterisation and tissues expression analysis of the goose (Anser cygnoides) vasoactive intestinal peptide (VIP) gene.Semantic proximity Read ↗

Mutational analysis of the human vasoactive intestinal peptide receptor subtype VPAC(2): role of basic residues in the second transmembrane helix.Semantic proximity Read ↗

Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.Semantic proximity Read ↗

The neuropeptide VIP modulates the neurotransmitter phenotype of cultured chick sympathetic neurons.Semantic proximity Read ↗

Functional splice variants of the type II G protein-coupled receptor (VPAC2) for vasoactive intestinal peptide in mouse and human lymphocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.