Article
Twitchin kinase inhibits muscle activity.
Molecular biology of the cell - 15 Jun 2017
Matsunaga Yohei, Hwang Hyundoo, Franke Barbara, Williams Rhys, Penley McKenna, Qadota Hiroshi, Yi Hong, Morran Levi T, Lu Hang, Mayans Olga, Benian Guy M
Abstract excerpt
Muscle sarcomeres contain giant polypeptides composed of multiple immunoglobulin and fibronectin domains and one or two protein kinase domains. Although binding partners for a number of this family's kinase domains have been identified, the catalytic necessity of these kinase domains remains unknown. In addition, various members of this kinase family are suspected pseudokinases with no or little activity. Here we...
Topics
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calmodulin-Binding Proteins
- Helminth Proteins
- Lysine
- Muscle Contraction
- Muscle Proteins
- Mutation
- Phosphorylation
- Protein Binding
- Protein Kinases
- Sarcomeres