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Article

Novel functional polymorphism in IGF-1 gene associated with multiple sclerosis: A new insight to MS.

Multiple sclerosis and related disorders - 1 Apr 2017

Shahbazi Majid, Abdolmohammadi Reza, Ebadi Hamid, Farazmandfar Touraj

Abstract excerpt

BACKGROUND: Interactions between several genes and environment may play a role in susceptibility to multiple sclerosis (MS). The IGF-1 plays a key role in proliferation, maintenance and survival of nerve cells. Therefore, we hypothesized that IGF-1 may be a target for prediction and control MS. We aimed to analysis IGF-1 gene promoter sequence, to investigate the effect of the single nucleotide variants on IGF-1...

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Identifiers

PMID: 28427698
DOI: 10.1016/j.msard.2017.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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