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Article

Relationship between NF-κB1 -94 ins/del ATTG polymorphism and susceptibility of multiple sclerosis in Iranian MS patients.

Neuroscience letters - 17 Jun 2013

Zahednasab Hamid, Mesbah-Namin Seyed Alireza, Sahraian Mohammad Ali, Balood Mohammad, Doosti Rozita

Abstract excerpt

Multiple sclerosis (MS) is one of the most common neurological diseases of the central nervous system (CNS) which is mediated by the autoimmune reactions against myelin sheath. Both genetic and environmental factors are thought to be involved in the pathogenesis of MS. NF-κB1 is one of the most important molecules which regulates the immune functions. NF-κB1 -94 ins/del ATTG promoter polymorphism is a...

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PMID: 23618653
DOI: 10.1016/j.neulet.2013.04.014

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