The analysis of correlation between IL-1B gene expression and genotyping in multiple sclerosis patients.

Abstract excerpt

IL-1B is released by monocytes, astrocytes and brain endothelial cells and seems to be involved in inflammatory reactions of the central nervous system (CNS) in multiple sclerosis (MS). This study aims to evaluate the expression level of IL-1B mRNA in peripheral blood mononuclear cells (PBMCs), genotype the rs16944 SNP and find out the role of this SNP on the expression level of IL-1B in MS patients. We found...

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• Case-Control Studies
• Interleukin-1beta
• Leukocytes, Mononuclear
• Multiple Sclerosis
• Polymorphism, Single Nucleotide