Article
GSTM1 and GSTT1 Genes are Associated With DNA Damage of p53 Gene in Coke-oven Workers.
Journal of occupational and environmental medicine - 1 Jun 2017
He Yuefeng, Qi Jun, He Fang, Zhang Yongchang, Wang Youlian, Zhang Ruobing, Li Gang
Abstract excerpt
OBJECTIVES: This study investigated whether variations in GSTT1 and GSTM1 gene are associated with the DNA damage level of p53 gene. METHODS: We quantified urinary 1-hydroxypyrene using high-performance liquid chromatography, and examined the DNA damage level of p53 gene by real-time quantitative PCR in 756 coke-oven workers. Multiplex PCR was used to detect the presence or absence of genes. RESULTS: DNA damage...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
