Soluble-HLA-E: A follow up biomarker in Takayasu arteritis, independent of HLA-E genotype.

doi:10.1111/1756-185X.13027

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Article

Soluble-HLA-E: A follow up biomarker in Takayasu arteritis, independent of HLA-E genotype.

International journal of rheumatic diseases - 1 Feb 2018

Goel Ruchika, Kabeerdoss Jayakanthan, Mohan Hindhumathi, Danda Sumita, Jayaseelan Visali, Kumar T Sathish, Jude John, Bacon Paul, Joseph George, Danda Debashish

Abstract excerpt

AIM: Disease activity assessment in Takayasu arteritis (TA) is challenging. Human leukocyte antigen E (HLA-E) is shed from endothelium into serum as a soluble molecule (sHLA-E) in response to inflammation. We aimed to study: (i) utility of sHLA-E as a biomarker of disease activity; and (ii) association of HLA-E polymorphism rs1264457 with clinical disease in Asian-Indian TA patients. MATERIALS AND METHODS: In...

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PMID: 28425192
DOI: 10.1111/1756-185X.13027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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