Article
Increased sHLA-G Is Associated with Improved COVID-19 Outcome and Reduced Neutrophil Adhesion.
Viruses - 17 Sept 2021
Bortolotti Daria, Gentili Valentina, Rizzo Sabrina, Schiuma Giovanna, Beltrami Silvia, Spadaro Savino, Strazzabosco Giovanni, Campo Gianluca, Carosella Edgardo D, Papi Alberto, Rizzo Roberta, Contoli Marco
Abstract excerpt
Human leukocyte antigen (HLA) is a group of molecules involved in inflammatory and infective responses. We evaluated blood sHLA-E and sHLA-G levels in hospitalized COVID-19 patients with respiratory failure and their relationship with clinical evolution, changes in endothelial activation biomarker profile, and neutrophil adhesion. sHLA-E, sHLA-G, and endothelial activation biomarkers were quantified by ELISA...
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