Article
The sulfilimine cross-link of collagen IV contributes to kidney tubular basement membrane stiffness.
American journal of physiology. Renal physiology - 1 Sept 2017
Bhave Gautam, Colon Selene, Ferrell Nicholas
Abstract excerpt
Basement membranes (BMs), a specialized form of extracellular matrix, underlie nearly all cell layers and provide structural support for tissues and interact with cell surface receptors to determine cell behavior. Both macromolecular composition and stiffness of the BM influence cell-BM interactions. Collagen IV is a major constituent of the BM that forms an extensively cross-linked oligomeric network. Its...
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