Article
Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype.
Kidney international - 1 Sept 2010
Pallier Annaick, Hillion Sophie, Danger Richard, Giral Magali, Racapé Maud, Degauque Nicolas, Dugast Emilie, Ashton-Chess Joanna, Pettré Ségolène, Lozano Juan José, Bataille Régis, Devys Anne, Cesbron-Gautier Anne, Braudeau Cécile, Larrose Catherine, Soulillou Jean-Paul, Brouard Sophie
Abstract excerpt
Several transplant patients maintain stable kidney graft function in the absence of immunosuppression. Here we compared the characteristics of their peripheral B cells to that of others who had stable graft function but were under pharmacologic immunosuppression, to patients with chronic rejection and to healthy volunteers. In drug-free long-term graft function (DF) there was a significant increase in both...
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